acne

TETRALYSAL®

Lymecycline

What is in this leaflet

This leaflet answers some common questions about TETRALYSAL. Please read this
leaflet carefully before you start taking the capsules. It does not contain all
the information available on this medicine. It does not take the place of
talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of
you taking TETRALYSAL against the benefits it might have for you. If you have
concerns about using this medicine ask your doctor or pharmacist.

ORATANE®

Isotretinoin 10 mg, 20 mg and 40 mg Capsules

What is in this leaflet

This leaflet answers some of the common questions about ORATANE capsules. It
does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks or
you taking ORATANE capsules against the benefit the medicine is expected to have
for you.

If you have any concerns about taking this medicine, ask your doctor or
pharmacist.

ISOTANE

Isotretinoin 10mg and 20mg Capsules

What is in this leaflet

This leaflet answers some common questions about ISOTANE. It does not contain
all the available information. It does not take the place of talking to your
doctor or pharmacist. All medicines have risks and benefits. Your doctor has
weighed the risks of you taking ISOTANE against the benefits they expect it will
have for you. If you have any concerns about taking this medicine, ask your
doctor or pharmacist. Keep this leaflet with the medicine. You may need to read
it again.

ESTELLE™-35 ED

Cyproterone acetate 2 mg and ethinyloestradiol 0.035 mg

What is in this leaflet

This leaflet answers some common questions about Estelle-35 ED. It does not
contain all the available information. It does not take the place of talking to
your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of
you taking Estelle-35 ED against the benefits this medicine is expected to have
for you.

If you have any concerns about taking this medicine, ask your doctor or
pharmacist.

Keep this leaflet with the medicine; you may need to read it again.

What ESTELLE-35 ED is used for

Estelle-35 ED is used to treat women who suffer from conditions arising from
increased secretion of or increased response to androgen (male) hormones. Such
conditions include acne, or moderately increased growth of facial and body hair
(hirsutism).

Estelle 35-ED should be withdrawn 3 to 4 cycles after the treated condition
has been completely resolved.

Estelle-35 ED provides effective oral contraception in women being treated
for androgen-dependent diseases.

Duac® Once Daily Gel

Active ingredients: clindamycin 1% w/w (as phosphate) and benzoyl peroxide
5% w/w

What is in this leaflet?

This leaflet answers some common questions about Duac Once Daily Gel.
It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have benefits and risks. Your doctor has weighed the benefits
of you using Duac Once Daily Gel against the risks he expects it may have
for you.

DOXINE

Doxycycline 100 mg tablets

What is in this leaflet

This leaflet answers some common questions about DOXINE tablets. It does not contain all the available information. It does not take the place of talking to your doctor and pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of using DOXINE against the benefits expected it will have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet. You may want to read it again.

DIFFERIN® TOPICAL GEL

Adapalene 0.1%

What is in this leaflet

This leaflet answers some common questions about DIFFERIN. Please read this
leaflet carefully before you start using the gel. It does not contain all the
information available on this medicine. It does not take the place of talking to
your doctor or pharmacist.

DIANE®35 ED

Cyproterone acetate 2mg and Ethinylestradiol 35mcg tablets

What is in this leaflet

Please read this leaflet carefully before you start using DIANE-35 ED. It
will advise you about how to take DIANE-35 ED properly and when to tell your
doctor about health-related conditions. If you have any questions or need more
advice, ask your doctor, professional health care provider or pharmacist.

What is DIANE-35 ED used for and how does it work

Each small active tablet contains a small amount of two different hormones.
These are cyproterone acetate (a progestogen with antiandrogenic properties) and
ethinylestradiol (an estrogen). Because of the small amounts of hormones,
DIANE-35 ED is considered a low-dose preparation. DIANE-35 ED also contains 7
large white inactive (placebo) tablets that do not contain any active
ingredients.

How does DIANE-35 ED work?

DIANE-35 ED is designed for the treatment of women who suffer from acne or
moderately increased growth of facial and body hair (hirsutism). These
conditions occur when there is over-production of male type hormones called
androgens. DIANE-35 ED contains two substances that act against the androgens,
cyproterone acetate and ethinylestradiol. The main ingredient, cyproterone
acetate, causes the body to produce less androgens and blocks the actions of
those that are still produced.

While DIANE-35 ED is being taken, the activity of the sebaceous glands which
play an important role in the development of acne and oily skin or seborrhoea,
is reduced. This leads - usually after 3 to 4 months of therapy - to the healing
of existing acne. Excessive greasiness of the hair and skin, which often
accompanies this condition, generally disappears earlier. Treatment with
DIANE-35 ED is also useful in women of child-bearing age who have mild forms of
hirsutism and in particular slightly increased facial hair although the results
do not usually become apparent until several months of use.

Other properties

As well as being an anti-androgen, cyproterone acetate has the properties of
a female sex-hormone (progestogen) and its combination with an estrogen (ethinylestradiol)
in DIANE-35 ED makes the preparation a highly effective oral contraceptive.
Therefore, if you normally use a contraceptive method, you will not need to use
it while taking DIANE-35 ED (except in the special circumstances described
later). Oral contraceptives must not be used with DIANE-35 ED.

In the treatment of women with polycystic ovary syndrome, DIANE-35 ED reduces
the signs of androgenization, leads to normalization of the hormone levels,
reduces cyst formation and ovarian volume and helps to restore regular
menstruation.

What is DIANE-35 ED used for?

DIANE-35 ED is used for the treatment of androgen-dependent diseases in
women, such as acne (where oral antibiotics or local treatment alone has not
been successful), androgenic alopecia and mild forms of hirsutism. It is
especially useful for pronounced forms of acne and those accompanied by
seborrhea or by inflammation or formation of nodes (acne papulopustulosa, acne
nodulocystica).

DIANE-35 ED is also used for oral contraception in women requiring treatment
for these androgenic conditions; it is not recommended just for contraception.
DIANE-35 ED is also indicated for the treatment of polycystic ovary syndrome.

BENZAC AC®

Benzoyl peroxide

What is in this leaflet

This leaflet answers some common questions about BENZAC. Please read this
leaflet carefully before you start using the gel. It does not contain all the
information available on this medicine. It does not take the place of talking to
your doctor or pharmacist.

All medicines have risks and benefits. If you have concerns about using this
medicine ask your doctor or pharmacist.

Keep this leaflet with your tube. You may wish to read it again later.

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